Faculty profile

Gennady Poda

Back to faculty

Assistant ProfessorStatusUniversity of Toronto

Gennady Poda

Assistant Professor

Status

Leslie Dan Faculty of Pharmacy

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
16 publications in the last five years, latest in 2026.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students. How applying works · What these words mean

Academic metrics

Publications

863

Citations

Collaborators

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them. What is the h-index?

Profiles and links

University Profile

Search on Google Scholar

Search on ResearchGate

OpenAlex

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2.
Journal of chemical information and modeling · 2026
Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.
Bioorganic & medicinal chemistry · 2026
Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.
Bioorganic & medicinal chemistry letters · 2026

All 31 publications

31 publications.

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2.

Herasymenko O, Silva M, Correy GJ, Abu-Saleh AAA, Ackloo S, Arrowsmith C, Ashworth A, Ban F, Beck H, Bishop KP, Bohórquez HJ, Bolotokova A, Breznik M, Chau I, Chen Y, Cherkasov A, Dehaen W, Della Corte D, Denzinger K, Doering NP, Edfeldt K, Edwards A, Fayne D, Gentile F, Gibson E, Gokdemir O, Gunnarsson A, Günther J, Irwin JJ, Jensen JH, Harding RJ, Hillisch A, Hoffer L, Hogner A, Hutchinson A, Kandwal S, Karlova A, Koirala K, Kotelnikov S, Kozakov D, Lee J, Lee S, Lessel U, Liu S, Liu X, Loppnau P, Meiler J, Moretti R, Moroz YS, Muvva C, Oprea TI, Paige B, Pandit A, Park K, Poda G, Protopopov MV, Pütter V, Ravichandran R, Rognan D, Rosta E, Sabnis Y, Scott T, Seitova A, Sharma P, Sindt F, Song M, Steinmann C, Stevens R, Talagayev V, Tararina VV, Tarkhanova O, Tingey D, Trant JF, Treleaven D, Tropsha A, Walters P, Wells J, Westermaier Y, Wolber G, Wortmann L, Zheng S, Fraser JS, Schapira M

Journal of chemical information and modeling20263 citationsOpen Access

DOI: 10.1021/acs.jcim.5c02441 PMID: 41565251

Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.

Watson IDG, Morin JA, Subramanian PR, Chau AM, Prakesch MA, Wilson BJ, Morshed MM, Joseph BB, Uehling DE, Poda G, Abibi A, Chan M, Cheung H, Griffin C, Mao V, Marcellus R, Strathdee C, Subramaniam R, Thériault BL, Winston J, Aman A, Kiyota T, Undzys E, Kuntz DA, Pomroy NC, Mamai A, Privé GG, Al-Awar R, Isaac MB

Bioorganic & medicinal chemistry20261 citations

DOI: 10.1016/j.bmc.2026.118575 PMID: 41621194

Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.

Mamai A, Morshed MM, Prakesch M, Poda G, Subramanian P, Chau AM, Watson IDG, Joseph B, Wilson B, Morin JA, Marcellus R, Theriault B, Mohammed M, Abibi A, Chan M, Kiyota T, Aman A, Subramaniam R, Strathdee C, Winston J, O'Meara J, Kuntz D, Pomroy NC, Uehling D, Isaac M, Privé GG, Al-Awar R

Bioorganic & medicinal chemistry letters2026

DOI: 10.1016/j.bmcl.2025.130471 PMID: 41241078

A Customizable Antibody Delivery Strategy Using Fc-Affinity Ligands

Daniela Isaacs-Bernal, Noor E. Bahsoun, Lia Huo, Gennady I. Poda, Dima Kozakov, Molly S. Shoichet

ACS Biomaterials Science & Engineering2026

DOI: 10.1021/acsbiomaterials.5c02112 PMID: 41789782

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.

Herasymenko O, Silva M, Abu-Saleh AAA, Ahmad A, Alvarado-Huayhuaz J, Arce OEA, Armstrong RJ, Arrowsmith C, Bachta KE, Beck H, Berta D, Bieniek MK, Blay V, Bolotokova A, Bourne PE, Breznik M, Brown PJ, Campbell ADG, Carosati E, Chau I, Cole DJ, Cree B, Dehaen W, Denzinger K, Dos Santos Machado K, Dunn I, Durai P, Edfeldt K, Edwards A, Fayne D, Felfoldi D, Friston K, Ghiabi P, Gibson E, Günther J, Gunnarsson A, Hillisch A, Houston DR, Jensen JH, Harding RJ, Harris KS, Hoffer L, Hogner A, Horton JT, Houliston S, Hultquist JF, Hutchinson A, Irwin JJ, Jukič M, Kandwal S, Karlova A, Katis VL, Kich RP, Kireev D, Koes D, Inniss NL, Lessel U, Liu S, Loppnau P, Lu W, Martino S, McGibbon M, Meiler J, Mettu A, Money-Kyrle S, Moretti R, Moroz YS, Muvva C, Newman JA, Obendorf L, Paige B, Pandit A, Park K, Perveen S, Pirie R, Poda G, Protopopov M, Pütter V, Ricci F, Roper NJ, Rosta E, Rzhetskaya M, Sabnis Y, Satchell KJF, Schmitt Kremer F, Scott T, Seitova A, Steinmann C, Talagayev V, Tarkhanova OO, Tatum NJ, Treleaven D, Velasque Werhli A, Walters WP, Wang X, Wells J, Wells G, Westermaier Y, Wolber G, Wortmann L, Zhang J, Zhao Z, Zheng S, Schapira M

Journal of chemical information and modeling202515 citationsOpen Access

DOI: 10.1021/acs.jcim.5c00535 PMID: 40539604

Ligand interaction landscape of transcription factors and essential enzymes in E. coli.

Peng H, Kotelnikov S, Egbert ME, Ofaim S, Stevens GC, Phanse S, Saccon T, Ignatov M, Dutta S, Istace Z, Moutaoufik MT, Aoki H, Kewalramani N, Sun J, Gong Y, Padhorny D, Poda G, Alekseenko A, Porter KA, Jones G, Rodionova I, Guo H, Pogoutse O, Datta S, Saier M, Crovella M, Vajda S, Moreno-Hagelsieb G, Parkinson J, Segre D, Babu M, Kozakov D, Emili A

Cell202514 citationsOpen Access

DOI: 10.1016/j.cell.2025.01.003 PMID: 39862855

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

Kimani SW, Noureldin M, Wilson B, Hoffer L, Green SR, Szewczyk MM, González-Álvarez H, Mohammed M, Chan M, Krausser C, Li ASM, Hajian T, Tucker S, Joshi D, Saraon P, Thériault B, Kim JS, Santhakumar V, Loppnau P, Li Y, Seitova A, Dong A, Kiyota T, Hammann T, Gehrtz P, Patel B, Rathod V, Vala A, Rout B, Jagodra P, Brown PJ, Aman A, Ramnauth J, Poda G, Uehling D, Arrowsmith CH, Barsyte-Lovejoy D, Marcellus R, Ackloo S, Mamai A, Al-Awar R, Halabelian L

Communications biology20254 citationsOpen Access

DOI: 10.1038/s42003-025-08491-0 PMID: 40683980

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity.

Mabanglo MF, Wilson B, Noureldin M, Kimani SW, Mamai A, Krausser C, González-Álvarez H, Srivastava S, Mohammed M, Hoffer L, Chan M, Avrumutsoae J, Li ASM, Hajian T, Tucker S, Green S, Szewczyk M, Barsyte-Lovejoy D, Santhakumar V, Ackloo S, Loppnau P, Li Y, Seitova A, Kiyota T, Wang JG, Privé GG, Kuntz DA, Patel B, Rathod V, Vala A, Rout B, Aman A, Poda G, Uehling D, Ramnauth J, Halabelian L, Marcellus R, Al-Awar R, Vedadi M

Nature communications202439 citationsOpen Access

DOI: 10.1038/s41467-024-54500-x PMID: 39580491

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

Li F, Ackloo S, Arrowsmith CH, Ban F, Barden CJ, Beck H, Beránek J, Berenger F, Bolotokova A, Bret G, Breznik M, Carosati E, Chau I, Chen Y, Cherkasov A, Corte DD, Denzinger K, Dong A, Draga S, Dunn I, Edfeldt K, Edwards A, Eguida M, Eisenhuth P, Friedrich L, Fuerll A, Gardiner SS, Gentile F, Ghiabi P, Gibson E, Glavatskikh M, Gorgulla C, Guenther J, Gunnarsson A, Gusev F, Gutkin E, Halabelian L, Harding RJ, Hillisch A, Hoffer L, Hogner A, Houliston S, Irwin JJ, Isayev O, Ivanova A, Jacquemard C, Jarrett AJ, Jensen JH, Kireev D, Kleber J, Koby SB, Koes D, Kumar A, Kurnikova MG, Kutlushina A, Lessel U, Liessmann F, Liu S, Lu W, Meiler J, Mettu A, Minibaeva G, Moretti R, Morris CJ, Narangoda C, Noonan T, Obendorf L, Pach S, Pandit A, Perveen S, Poda G, Polishchuk P, Puls K, Pütter V, Rognan D, Roskams-Edris D, Schindler C, Sindt F, Spiwok V, Steinmann C, Stevens RL, Talagayev V, Tingey D, Vu O, Walters WP, Wang X, Wang Z, Wolber G, Wolf CA, Wortmann L, Zeng H, Zepeda CA, Zhang KYJ, Zhang J, Zheng S, Schapira M

Journal of chemical information and modeling202429 citationsOpen Access

DOI: 10.1021/acs.jcim.4c01267 PMID: 39499532

Discovery of Nanomolar DCAF1 Small Molecule Ligands.

Li ASM, Kimani S, Wilson B, Noureldin M, González-Álvarez H, Mamai A, Hoffer L, Guilinger JP, Zhang Y, von Rechenberg M, Disch JS, Mulhern CJ, Slakman BL, Cuozzo JW, Dong A, Poda G, Mohammed M, Saraon P, Mittal M, Modh P, Rathod V, Patel B, Ackloo S, Santhakumar V, Szewczyk MM, Barsyte-Lovejoy D, Arrowsmith CH, Marcellus R, Guié MA, Keefe AD, Brown PJ, Halabelian L, Al-Awar R, Vedadi M

Journal of medicinal chemistry202366 citationsOpen Access

DOI: 10.1021/acs.jmedchem.2c02132 PMID: 36948210

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

Something wrong or missing on this profile? Suggest a correction

Gennady Poda

Research

Latest papers

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2.

Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.

Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.

A Customizable Antibody Delivery Strategy Using Fc-Affinity Ligands

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.

Ligand interaction landscape of transcription factors and essential enzymes in E. coli.

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity.

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

Discovery of Nanomolar DCAF1 Small Molecule Ligands.

Frequent collaborators

Rima Al-awar

David Uehling

Ahmed Aman

Cheryl Arrowsmith

Gil Privé

Levon Halabelian

Gilbert Privé

Masoud Vedadi

Matthieu Schapira

Aled Edwards

Dalia Barsyte-Lovejoy

Rachel Harding

Natasha Leighl

Robert Batey

Igor Stagljar

Frank Sicheri

Henry Krause

Francesco Gentile

Brian Wilson

Ming-Sound Tsao

Artem Cherkasov

Adrian Sacher

Carolyn Cummins

Andrei Yudin

Hui Peng

Mohan Babu

Gennady Poda

Research

Latest papers

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2.

Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.

Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.

A Customizable Antibody Delivery Strategy Using Fc-Affinity Ligands

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.

Ligand interaction landscape of transcription factors and essential enzymes in E.&#xa0;coli.

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity.

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

Discovery of Nanomolar DCAF1 Small Molecule Ligands.

Frequent collaborators

Rima Al-awar

David Uehling

Ahmed Aman

Cheryl Arrowsmith

Gil Privé

Levon Halabelian

Gilbert Privé

Masoud Vedadi

Matthieu Schapira

Aled Edwards

Dalia Barsyte-Lovejoy

Rachel Harding

Natasha Leighl

Robert Batey

Igor Stagljar

Frank Sicheri

Henry Krause

Francesco Gentile

Brian Wilson

Ming-Sound Tsao

Artem Cherkasov

Adrian Sacher

Carolyn Cummins

Andrei Yudin

Hui Peng

Mohan Babu

Ligand interaction landscape of transcription factors and essential enzymes in E. coli.