Robert Nadon, McGill University

Research

Read how they describe their research on their McGill University profile.

Latest papers

Accurate deep learning off-target prediction with novel sgRNA-DNA sequence encoding in CRISPR-Cas9 gene editing.
Bioinformatics (Oxford, England) · 2021
Four erroneous beliefs thwarting more trustworthy research.
eLife · 2019
Exact replication: Foundation of science or game of chance?
PLoS biology · 2019

All 30 publications

Latest funding

Projets de recherche en équipe
FRQNT · 2018 · Principal investigator
$204,140
Defining and Applying "Oncometabolism": A team approach in understanding and translating the Warburg effect from oncogenic and tumour suppressing activities.
CIHR · 2010 · Co-investigator
The CIHR/FRSQ Training Program in Cancer Research at McGill
CIHR · 2008 · Co-investigator
$975,000

All 3 grants and awards

30 publications.

01

Accurate deep learning off-target prediction with novel sgRNA-DNA sequence encoding in CRISPR-Cas9 gene editing.

Charlier J, Nadon R, Makarenkov V

Bioinformatics (Oxford, England)2021

DOI: 10.1093/bioinformatics/btab112 PMID: 33599251

02

Four erroneous beliefs thwarting more trustworthy research.

Yarborough M, Nadon R, Karlin DG

eLife2019

DOI: 10.7554/elife.45261 PMID: 31355746

03

Exact replication: Foundation of science or game of chance?

Piper SK, Grittner U, Rex A, Riedel N, Fischer F, Nadon R, Siegerink B, Dirnagl U

PLoS biology2019

DOI: 10.1371/journal.pbio.3000188 PMID: 30964856

04

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.

Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, Mechawar N, Turecki G, Lacaille JC, Gobbi G, Sonenberg N

Nature communications201885 citationsOpen Access

DOI: 10.1038/s41467-018-04883-5 PMID: 29941989

05

Statistics and Biology: Not Your Average Relationship.

Nadon R, Kayne P

SLAS discovery : advancing life sciences R & D2018First author

DOI: 10.1177/2472555218769904 PMID: 29781352

06

Identification and Correction of Additive and Multiplicative Spatial Biases in Experimental High-Throughput Screening.

Mazoure B, Caraus I, Nadon R, Makarenkov V

SLAS discovery : advancing life sciences R & D2018

DOI: 10.1177/2472555217750377 PMID: 29346010

07

Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies.

Mazoure B, Nadon R, Makarenkov V

Scientific reports2017

DOI: 10.1038/s41598-017-11940-4 PMID: 28931934

08

Detecting and removing multiplicative spatial bias in high-throughput screening technologies.

Caraus I, Mazoure B, Nadon R, Makarenkov V

Bioinformatics (Oxford, England)2017

DOI: 10.1093/bioinformatics/btx327 PMID: 28633418

09

Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.

Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, Bourque G, Yang XJ, Tian B, Stunnenberg HG, Yamanaka Y, Blencowe BJ, Giguère V, Sonenberg N

Proceedings of the National Academy of Sciences of the United States of America201677 citationsOpen Access

DOI: 10.1073/pnas.1615540113 PMID: 27791185

10

Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3.

Tsukumo Y, Alain T, Fonseca BD, Nadon R, Sonenberg N

Nature communications201651 citationsOpen Access

DOI: 10.1038/ncomms11776 PMID: 27319316

Projets de recherche en équipe

Principal investigatorFRQNT2018Projets de recherche en équipe

Principal investigators: Nadon, Robert

Keywords: high-throughput screening, algorithm development, RNAi; Techniques, mesures et systèmes; Technologies biomédicales; Fondements de la pensée scientifique

$204,140

Defining and Applying "Oncometabolism": A team approach in understanding and translating the Warburg effect from oncogenic and tumour suppressing activities.

Co-investigatorCIHR2010Team Grant: Terry Fox New Frontiers Program in Cancer

Principal investigators: Tremblay, Michel L; Jones, Russell G; Pause, Arnim P; Sonenberg, Nahum; St-Pierre, Julie

Keywords: Amp Kinase; Anima Models Phenotyping; Bioenergetics; Cancer Prevention And Therapies; Cell Signaling; Oncometabolism; Protein Synthesis; Transcription Regulation Of Metabolic Genes; Tyrosine Phosphorylation; Warburg Effect

The CIHR/FRSQ Training Program in Cancer Research at McGill

Co-investigatorCIHR2008Training Grant

Principal investigators: Tremblay, Michel L; Miller, Wilson H

Keywords: Cancer Research; Collaborative; Ethics; Multidisciplinary Program; Scientific Management; Training; Translational Research

$975,000

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Gustavo Turecki and Naguib Mechawar: 170 shared papers
Nahum Sonenberg and Tommy Alain: 56 shared papers
Nahum Sonenberg and Jerry Pelletier: 52 shared papers
Nahum Sonenberg and Arkady Khoutorsky: 50 shared papers
Nahum Sonenberg and Ivan Topisirovic: 48 shared papers
Gabriella Gobbi and Stefano Comai: 45 shared papers
Ivan Topisirovic and Tommy Alain: 26 shared papers
Nahum Sonenberg and Argel Aguilar-Valles: 21 shared papers
Nahum Sonenberg and Vijendra Sharma: 10 shared papers
Arkady Khoutorsky and Vijendra Sharma: 9 shared papers
Vincent Giguere and Guillaume Bourque: 8 shared papers
Tommy Alain and Arkady Khoutorsky: 7 shared papers
Nahum Sonenberg and Vincent Giguere: 6 shared papers
Nahum Sonenberg and Gabriella Gobbi: 6 shared papers
Jerry Pelletier and Ivan Topisirovic: 6 shared papers
Nahum Sonenberg and Robert Nadon: 5 shared papers
Gabriella Gobbi and Argel Aguilar-Valles: 5 shared papers
Maxime Bouchard and Yojiro Yamanaka: 5 shared papers
Nahum Sonenberg and Benjamin Blencowe: 4 shared papers
Vincent Giguere and Arkady Khoutorsky: 4 shared papers
Gabriella Gobbi and Gustavo Turecki: 4 shared papers
Nahum Sonenberg and Yojiro Yamanaka: 3 shared papers
Vincent Giguere and Xiang-Jiao Yang: 3 shared papers
Maxime Bouchard and Guillaume Bourque: 3 shared papers
Guillaume Bourque and Arkady Khoutorsky: 3 shared papers
Guillaume Bourque and Yojiro Yamanaka: 3 shared papers
Jerry Pelletier and Tommy Alain: 3 shared papers
Jerry Pelletier and Robert Nadon: 3 shared papers
Arkady Khoutorsky and Argel Aguilar-Valles: 3 shared papers
Nahum Sonenberg and Xiang-Jiao Yang: 2 shared papers
Nahum Sonenberg and Naguib Mechawar: 2 shared papers
Nahum Sonenberg and Stefano Comai: 2 shared papers
Robert Kearney and Robert Nadon: 2 shared papers
Gustavo Turecki and Guillaume Bourque: 2 shared papers
Gustavo Turecki and Stefano Comai: 2 shared papers
Xiang-Jiao Yang and Arkady Khoutorsky: 2 shared papers
Argel Aguilar-Valles and Vijendra Sharma: 2 shared papers
Vincent Giguere and Maxime Bouchard: 1 shared paper
Vincent Giguere and Benjamin Blencowe: 1 shared paper
Vincent Giguere and Robert Nadon: 1 shared paper
Indra Gupta and Maxime Bouchard: 1 shared paper
Indra Gupta and Yojiro Yamanaka: 1 shared paper
Indra Gupta and Robert Nadon: 1 shared paper
Robert Kearney and David Thomas: 1 shared paper
Gabriella Gobbi and Naguib Mechawar: 1 shared paper
Gabriella Gobbi and Robert Nadon: 1 shared paper
Maxime Bouchard and Robert Nadon: 1 shared paper
Gustavo Turecki and Robert Nadon: 1 shared paper
Benjamin Blencowe and Xiang-Jiao Yang: 1 shared paper
Benjamin Blencowe and Robert Nadon: 1 shared paper
David Thomas and Jerry Pelletier: 1 shared paper
David Thomas and Robert Nadon: 1 shared paper
Xiang-Jiao Yang and Robert Nadon: 1 shared paper
Guillaume Bourque and Robert Nadon: 1 shared paper
Ivan Topisirovic and Robert Nadon: 1 shared paper
Naguib Mechawar and Robert Nadon: 1 shared paper
Tommy Alain and Robert Nadon: 1 shared paper
Arkady Khoutorsky and Robert Nadon: 1 shared paper
Yojiro Yamanaka and Robert Nadon: 1 shared paper
Argel Aguilar-Valles and Robert Nadon: 1 shared paper
Vijendra Sharma and Robert Nadon: 1 shared paper
Stefano Comai and Robert Nadon: 1 shared paper
Robert Nadon and Ernest Lo: 1 shared paper

Department of Biochemistry
Department of Psychiatry
Department of Human Genetics
Department of Biomedical Engineering
Department of Neuroscience
Faculty of Dental Medicine and Oral Health Sciences
Donnelly Centre for Cellular and Biomolecular Research
Other

1 shared papers, latest 2006

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Subject: Prospective PhD student Dear Professor Nadon, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Accurate deep learning off-target prediction with novel sgRNA-DNA sequence encoding in CRISPR-Cas9 gene editing." (2021), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]