Faculty profile

Dan Winer

Scientist, Division of Advanced Diagnostics - Metabolism Toronto General Research InstituteDivision of Advanced Diagnostics - Metabolism Toronto General Research InstituteUniversity of Toronto

Dan Winer

Scientist, Division of Advanced Diagnostics - Metabolism Toronto General Research Institute

Division of Advanced Diagnostics - Metabolism Toronto General Research Institute

University of Toronto

Toronto, Ontario, Canada

Supervision signals

This is a research or leadership role; ask the department whether it includes supervision.
55 publications in the last five years, latest in 2026.
Senior (last) author on 13 recent papers, a sign of leading a research group.

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Academic metrics

131

Publications

14,187

Citations

Collaborators

Publications by year

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Adipocyte caspase-8 but not RIPK3 promotes adiposity.
Cell death discovery · 2026
Immunological biomarkers of aging
The Journal of Immunology · 2025
Astroimmunology: the effects of spaceflight and its associated stressors on the immune system
Nature reviews. Immunology · 2025 · first author

All 131 publications

131 publications.

Adipocyte caspase-8 but not RIPK3 promotes adiposity.

Chan CK, Aslam R, Yang F, Panesar A, Hakem A, Hakem R, Gaisano HY, Winer DA, Luk CT

Cell death discovery2026Open Access

DOI: 10.1038/s41420-026-03201-z PMID: 42337230

Immunological biomarkers of aging

Fei Wu, Wei‐Chieh Mu, Nikola T. Markov, Matías Fuentealba, Heather Halaweh, Fiona Senchyna, Max Manwaring-Mueller, Daniel A. Winer, David Furman

The Journal of Immunology202525 citationsOpen Access

DOI: 10.1093/jimmun/vkae036 PMID: 40443365

Astroimmunology: the effects of spaceflight and its associated stressors on the immune system

Daniel A. Winer, Huixun Du, JangKeun Kim, Veronica Chang, Marissa Burke, Shawn Winer, Sylvain V. Costes, Jean‐Pol Frippiat, Clarence Sams, Amber M. Paul, Honglu Wu, Oliver Ullrich, Sarah Baatout, Afshin Beheshti, Christopher E. Mason, Alexander Choukèr, Brian E. Crucian

Nature reviews. Immunology202516 citationsFirst authorOpen Access

DOI: 10.1038/s41577-025-01226-6 PMID: 41102553

Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts.

Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA

GeroScience202512 citationsSenior authorOpen Access

DOI: 10.1007/s11357-025-01507-x PMID: 39826027

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Pooja Raj Devrukhkar, Mark A. Watson, Bikem Soygur, Fei Wu, Joanna Bons, Hannah Anvari, Tomiris Atazhanova, Nicholas G. Martin, Tommy Tran, Kevin Schneider, Jacob Rose, Daniel A. Winer, Elisheva D. Shanes, Mary Ellen Pavone, Judith Campisi, David Furman, Simon Melov, Birgit Schilling, Francesca Elizabeth Duncan

Aging Cell202511 citationsOpen Access

DOI: 10.1111/acel.70111 PMID: 40452152

Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.

Makhijani P, Valentino TR, Manwaring-Mueller M, Emani R, Mu WC, Aguirre CG, Tan CR, Rane A, Wilson KA, Kifle A, Chen N, Du H, Wu F, Ng JHY, Ambrose BD, Ashok Kumaar PV, Khan S, Winer S, Wang C, Mortha A, Furman D, Schilling B, Ellerby LM, Rojas OL, Andersen JK, Winer DA

Cell reports20258 citationsSenior authorOpen Access

DOI: 10.1016/j.celrep.2025.116109 PMID: 40885186

Aging and immunity

Christoph A. Thaiss, Ye F. Tian, Daniel A. Winer, Michelle A. Linterman, Adrian Liston, Corina Amor, Scott W Lowe, Guang‐Hui Liu

Immunity20255 citations

DOI: 10.1016/j.immuni.2025.10.019 PMID: 41223838

Wheat Fiber Suppresses Development of Colitis via Microbiota-Mediated Fermentation-Independent Metabolites that Reprogram Intestinal Macrophages

Seong‐Eun Kim, Rachael Ott, Alexis Bretin, Hirohito Abo, Yanling Wang, Yadong Wang, Shawn Winer, Daniel A. Winer, Lavanya Reddivari, Stacey L. Heaver, Ruth E. Ley, Michael Pellizzon, Vu L. Ngo, Andrew T. Gewirtz

SSRN Electronic Journal20251 citationsOpen Access

DOI: 10.2139/ssrn.5220090

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Seong-Eun Kim, Hirohito Abo, Yanling Wang, Shawn Winer, Daniel A. Winer, Michael Pellizzon, Vu L. Ngo, Andrew T. Gewirtz

Mucosal Immunology20251 citationsOpen Access

DOI: 10.1016/j.mucimm.2025.12.003 PMID: 41443299

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Seong‐Eun Kim, Hirohito Abo, Yanling Wang, Shawn Winer, Daniel A. Winer, Michael Pellizzon, Vu L. Ngo, Andrew T. Gewirtz

bioRxiv (Cold Spring Harbor Laboratory)20251 citationsOpen Access

DOI: 10.1101/2025.03.31.646427

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Dan Winer

Research

Latest papers

Adipocyte caspase-8 but not RIPK3 promotes adiposity.

Immunological biomarkers of aging

Astroimmunology: the effects of spaceflight and its associated stressors on the immune system

Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts.

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.

Aging and immunity

Wheat Fiber Suppresses Development of Colitis via Microbiota-Mediated Fermentation-Independent Metabolites that Reprogram Intestinal Macrophages

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Frequent collaborators

Daniel Winer

Shawn Winer

Sue Tsai

Minna Woo

Cynthia Luk

Dana Philpott

Shereen Ezzat

Clinton Robbins

Arthur Mortha

Xavier Clemente-Casares

Stephen Girardin

Tak Mak

Shannon Dunn

David Brooks

Annie Shrestha

Herbert Gaisano

Ozgur Mete

Amit Bar-Or

Myron Cybulsky

Jennifer Gommerman

Allan Okrainec

Razq Hakem

Dan Winer

Research

Latest papers

Adipocyte caspase-8 but not RIPK3 promotes adiposity.

Immunological biomarkers of aging

Astroimmunology: the effects of spaceflight and its associated stressors on the immune system

Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts.

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Amyloid-&#x3b2;-driven Alzheimer's disease reshapes the colonic immune system in mice.

Aging and immunity

Wheat Fiber Suppresses Development of Colitis via Microbiota-Mediated Fermentation-Independent Metabolites that Reprogram Intestinal Macrophages

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Frequent collaborators

Daniel Winer

Shawn Winer

Sue Tsai

Minna Woo

Cynthia Luk

Dana Philpott

Shereen Ezzat

Clinton Robbins

Arthur Mortha

Xavier Clemente-Casares

Stephen Girardin

Tak Mak

Shannon Dunn

David Brooks

Annie Shrestha

Herbert Gaisano

Ozgur Mete

Amit Bar-Or

Myron Cybulsky

Jennifer Gommerman

Allan Okrainec

Razq Hakem

Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.