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Brent Derry

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ProfessorDepartment of Molecular GeneticsUniversity of Toronto

Brent Derry

Professor

Department of Molecular Genetics

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Tier 1 Canada Research Chair in Animal Models of Human Disease

Supervision signals

Professors usually supervise graduate students in their department's programs.
15 publications in the last five years, latest in 2025.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CRC).

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

106

Publications

4,628

Citations

Collaborators

Grants

Publications by year

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Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development
PubMed · 2025 · senior author
CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans.
Heredity · 2025 · senior author
A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integrity
bioRxiv (Cold Spring Harbor Laboratory) · 2025 · senior author

All 106 publications

Latest funding

Canada Research Chair in Animal Models of Human Disease
CRC · Principal investigator

All 1 grants and awards

106 publications.

Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development

Matthew Eroglu, W. Brent Derry

PubMed2025Senior authorOpen Access

DOI: 10.17912/micropub.biology.001557 PMID: 40191442

CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans.

Webster R, Quintana M, Yu B, Fluke S, Kafri R, Derry WB

Heredity2025Senior author

DOI: 10.1038/s41437-025-00769-7 PMID: 40383750

A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integrity

Anson Sathaseevan, Rhea Ahluwalia, Bin Yu, Claudia Makhenko-Tang, Haruka Nishimura, Alexander Leong, Kenneth Y. Kwan, W. Brent Derry

bioRxiv (Cold Spring Harbor Laboratory)2025Senior authorOpen Access

DOI: 10.1101/2025.07.01.662614 PMID: 40631188

Robotic microinjection enables large-scale transgenic studies of Caenorhabditis elegans.

Pan P, Zoberman M, Zhang P, Premachandran S, Bhatnagar S, Pilaka-Akella PP, Sun W, Li C, Martin C, Xu P, Zhang Z, Li R, Hung W, Tang H, MacGillivray K, Yu B, Zuo R, Pe K, Qin Z, Wang S, Li A, Derry WB, Zhen M, Saltzman AL, Calarco JA, Liu X

Nature communications202422 citationsOpen Access

DOI: 10.1038/s41467-024-53108-5 PMID: 39397017

Noncanonical inheritance of phenotypic information by protein amyloids

Matthew Eroglu, Tanner Zocher, Jacob McAuley, Rachel Webster, Maggie Z. X. Xiao, Bin Yu, Calvin A. Mok, W. Brent Derry

Nature Cell Biology202422 citationsSenior author

DOI: 10.1038/s41556-024-01494-9 PMID: 39223373

The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation.

Xiao YX, Lee SY, Aguilera-Uribe M, Samson R, Au A, Khanna Y, Liu Z, Cheng R, Aulakh K, Wei J, Farias AG, Reilly T, Birkadze S, Habsid A, Brown KR, Chan K, Mero P, Huang JQ, Billmann M, Rahman M, Myers C, Andrews BJ, Youn JY, Yip CM, Rotin D, Derry WB, Forman-Kay JD, Moses AM, Pritišanac I, Gingras AC, Moffat J

Cell reports202418 citationsOpen Access

DOI: 10.1016/j.celrep.2024.114417 PMID: 38980795

MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans

Evelyn M. Popiel, Rhea Ahluwalia, Stefan Schuetz, Bin Yu, W. Brent Derry

Development20241 citationsSenior authorOpen Access

DOI: 10.1242/dev.202772 PMID: 39494605

CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans

Rachel Webster, Maria L. Quintana, Ran Kafri, W. Brent Derry

bioRxiv (Cold Spring Harbor Laboratory)2024Senior authorOpen Access

DOI: 10.1101/2024.01.25.577258

TSC22D , WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing

Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe, Reuben Samson, Aaron Au, Yukti Khanna, Zetao Liu, Ran Cheng, Kamaldeep Aulakh, Jiarun Wei, Adrian Granda Farias, Taylor Reilly, Andrea Habsid, Kevin R. Brown, Katherine Chan, Patricia Mero, Jie Qi Huang, Maximilian Billmann, Mahfuzur Rahman, Chad L. Myers, Brenda Andrews, Ji‐Young Youn, Christopher M. Yip, Daniela Rotin, W. Brent Derry, Julie Deborah Forman-Kay, Alan M Moses, Iva Pritišanac, Anne‐Claude Gingras, Jason Moffat

bioRxiv (Cold Spring Harbor Laboratory)2024Open Access

DOI: 10.1101/2024.02.13.579840

MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans

Evelyn M. Popiel, W. Brent Derry

bioRxiv (Cold Spring Harbor Laboratory)2024Senior authorOpen Access

DOI: 10.1101/2024.01.25.577256

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Brent Derry

Research

Latest papers

Latest funding

Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development

CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans.

A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integrity

Robotic microinjection enables large-scale transgenic studies of Caenorhabditis elegans.

Noncanonical inheritance of phenotypic information by protein amyloids

The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation.

MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans

CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans

TSC22D , WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing

MRCK-1 activates non-muscle myosin for outgrowth of a unicellular tube in Caenorhabditis elegans

Canada Research Chair in Animal Models of Human Disease

Frequent collaborators

William Derry

Anne-Claude Gingras

Frank Sicheri

Ran Kafri

Radhey Gupta

Mei Zhen

Michael Taylor

Mohan Babu

James Ellis

Alan Moses

Daniel Shun Chung Yang

Jack Greenblatt

Ian Scott

Poul Sorensen

Brenda Andrews

Christopher Yip

Daniela Rotin

John Parkinson

Andrew Emili

Jason Moffat

Julie Forman-Kay